(46)

A general strategy for the synthesis of taxane diterpenes

L. Pan, F. Schneider, M. Ottenbruch, R. Wiechert, T. List, P. Schoch, B. Mertes, T. Gaich, Nature 2024, 632, 543-549.

(45)

Enantioselective Total Synthesis of (+)-Pepluanol A

P. Yuan and T. Gaich, Org. Lett. 2022, 24, 26, 4717–4721.

(44)

Ten-Step Asymmetric Total Synthesis of (+)-Pepluanol A

P. Yuan, C. K. G. Gerlinger, J. Herberger, T. Gaich J. Am. Chem. Soc. 2021, 143 (31), 11934–11938

(43)

The Chemistry of Nonclassical Taxane Diterpene

F. Schneider, L. Pan, M. Ottenbruch, T. List, T. Gaich, Acc. Chem. Res. 2021, 54 (10), 2347–2360

(42)

Total Synthesis of the Diterpene Waihoensene

 L.-C. Rosenbaum, M. Häfner, T. Gaich Angew. Chem. Int. Ed 2020, 60 (6), 2939-2942.

(41)

Light-switchable anchors on magnetized biomorphic microcarriers

 J. Opel, L.-C. Rosenbaum, J. Brunner, A. Staiger, R. Zimmermanns, M. Kellermeier, T. Gaich, H. Cölfen,  J.-M. García-Ruiz, J. Mater. Chem. B 2020, 8, 4831-4835.

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Total synthesis of the complex taxane diterpene canataxpropellane

F. Schneider, K. Samarin, S. Zanella, T. Gaich, Science 2020, 367 (6478), 676–681.

Mentioned in Organic Chemistry Highlights:

Other Methods for Carbocyclic Construction: Aspidodispermine (Heretsch), Lepadiformine A (Tokuyama), Farnesin (Gao), Ganocin B (Zhao), Dankasterone B (Heretsch), Canataxpropellane (Gaich)

Org. Chem. Highlights 2020, December 28.

The synthesis was featured in C&EN, Chemistry World, Angew. Chem & Synfacts.

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An Unexpected Transannular [4+2] Cycloaddition during the Total Synthesis of (+)-Norcembrene 5

M. Breunig, P. Yuan, T. Gaich, Angew. Chem. Int. Ed. 2020, 59 (14), 5521–5525.

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Enantioselective Synthesis of Cyclohepta[b]indoles via Pd-Catalyzed Cyclopropane C(sp3)–H Activation as a Key Step

M. Häfner, Y. M. Sokolenko, P. Gamerdinger, E. Stempel, T. Gaich, Org. Lett. 2019, 21 (18), 7370–7374.

(37)

Structure-Pattern-Based Total Synthesis

C. K. G. Gerlinger,  T. Gaich, Chem. Eur. J. 2019,
25 (46), 10782–10791.

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Gram-Scale Total Synthesis of Sarpagine Alkaloids and Non-Natural Derivatives

H. Rebmann, C. K. G. Gerlinger,  T. Gaich, Chem. Eur. J. 2019, 25 (11), 2704–2707. (Hot Paper)

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Total Synthesis of Parvineostemonine by Structure Pattern
Recognition: A Unified Approach to Stemona and Sarpagine Alkaloids

C. K. G. Gerlinger, S. Krüger, T. Gaich, Chem. Eur. J. 2018, 24 (16), 3994–3997.

Mentioned in Organic Chemistry Highlights:

Alkaloid Synthesis: Lentiginosine, Sparteine, Pancracine, Akuammiline, Parvineostemonine, Huperzine R

Organic Chemistry Highlights 2018, November 19.

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Methoxatin as a Target in Total Synthesis

B. Schröder, T. Gaich, Synthesis 2017, 49 (8), 1746–1756.

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Formal Total Synthesis of (±)-Strictamine by [2,3]-Sigmatropic Stevens Rearrangements

R. Eckermann, M. Breunig, T. Gaich, Chem. Eur. J. 2017, 23 (16), 3938–3949.

Mentioned in Organic Chemistry Highlights:

Alkaloid Synthesis: Strictamine, Corymine, Lycodoline, Mitomycin K, Lasubine I

Organic Chemistry Highlights 2017, November 20.

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Cyclohepta[b]indoles: A Privileged Structure Motif in Natural Products and Drug Design

E. Stempel, T. Gaich, Acc. Chem. Res. 2016, 49 (11), 2390–2402.

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The Rhazinilam-Leuconoxine-Mersicarpine Triad of Monoterpenoid Indole Alkaloids

M. Pfaffenbach, T. Gaich, in The Alkaloids: Chemistry and Biology Vol. 77,
Chapter 4: Aspidosperma Derived Alkaloids: The Leuconolam-Leuconoxine-Mersicarpine Triad, Academic Press, accepted.
ISBN: 9780128111246

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Synthesis of Indolophanes via Photochemical Macrocyclization

M. Pfaffenbach, A. Roller, T. Gaich, Chem. Eur. J. 2016, 22 (25), 8444–8447.

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The Diaza[5.5.6.6]fenestrane Skeleton-Synthesis of Leuconoxine Alkaloids

M. Pfaffenbach, T. Gaich, Chem. Eur. J. 2015, 22 (11), 3600–3610.

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A Flexible Route to Indole Scaffolds – Formal Synthesis of (±)-Mersicarpine

M. Pfaffenbach, T. Gaich, Eur. J. Org. Chem. 2015, 16, 3427–3429.

(23)

A Photoinduced Cyclization Cascade—Total Synthesis of (−)-Leuconoxine

M. Pfaffenbach, T. Gaich, Chem. Eur. J. 2015, 21 (17), 6355–6357.

(22)

Enantioselective, Protecting-Group-Free Total Synthesis of Sarpagine Alkaloids—A Generalized Approach

S. Krüger, T. Gaich, Angew. Chem. Int. Ed. 2015, 54 (1), 315–317.

Mentioned in Synfacts:

Synthesis of Sarpagine Alkaloids

Synfacts 2015, 11 (1), 7.

(21)

Light-Mediated Total Synthesis of 17-Deoxyprovidencin

N. Tölle, H. Weinstabl, T. Gaich, J.  Mulzer, Angew. Chem. Int. Ed. 2014, 53 (15), 3859–3862.

(20)

Recent applications of the divinylcyclopropane–cycloheptadiene rearrangement in organic synthesis

S. Krüger, T. Gaich, Beilstein J. Org. Chem. 2014, 10, 163–193.

(19)

The Witkop Cyclization: A Photoinduced C—H Activation of the Indole System

P. Gritsch, C. Leitner, M. Pfaffenbach, T. Gaich, Angew. Chem. Int. Ed. 2014, 53 (5), 1208–1217.

(18)

Enantioselective Synthesis of Cyclohepta[b]indoles: Gram-Scale Synthesis of (S)-SIRT1-Inhibitor IV

P. Gritsch, E. Stempel, T. Gaich, Org. Lett. 2013, 15 (21), 5472–5475.

Mentioned in Synfacts:

Synthesis of a SIRT1 Inhibitor

Synfacts 2014, 10 (1), 12.

(17)

The Akuammiline Alkaloids: Origin and Synthesis

R. Eckermann, T. Gaich, Synthesis 2013, 45, 2813–2823.

(16)

How to ‘Cope’ with the Prenylation of the Indole C4-Position

D. Schwarzer, P. Gritsch, T. Gaich, Synlett 2013, 24, 1025–1031.

(14)

Mimicking Dimethylallyltryptophan Synthase: Experimental Evidence for a Biosynthetic Cope Rearrangement Process

D. Schwarzer, P. Gritsch, T. Gaich, Angew. Chem. Int. Ed. 2012, 51 (46), 11514–11516.

(13)

Biomimetic Synthesis of Alkaloids with a Modified Indole Nucleus

T. Gaich, J. Mulzer, in Biomimetic Organic Synthesis, Wiley-VCH Verlag, Weinheim, 2012, 149–180
ISBN: 9783527325801

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Enantioselective Total Syntheses of (−)-Palau’amine, (−)-Axinellamines, and (−)-Massadines

I. B. Seiple, S. Su, I. S. Young, A. Nakamura, J. Yamaguchi, L. Jorgensen, R. A. Rodriguez, D. P. O'Malley, T. Gaich, M. Koeck, P. S. Baran, J. Am. Chem. Soc. 2011, 133 (37), 14710–14726.

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From Silphinenes to Penifulvins: A Biomimetic Approach to Penifulvins B and C

T. Gaich, J. Mulzer, Org. Lett. 2010, 12 (2), 272–275.

(10)

Aiming for the Ideal Synthesis

T. Gaich, P. S. Baran, J. Org. Chem. 2010, 75 (14), 4657–4673.

(9)

Total Synthesis of (−)-Penifulvin A, an Insecticide with a Dioxafenestrane Skeleton

T. Gaich, J. Mulzer, J. Am. Chem. Soc. 2009, 131 (2), 452–453.

(8)

Synthetic Efforts Towards the Synthesis of the Complex Diterpene Providencin

T. Gaich, H. Weinstabl, J. Mulzer, Synlett 2009, 9, 1357–1366.

(7)

It All Began with an Error: The Nomofungin/Communesin Story

P. Siengalewicz, T. Gaich, J. Mulzer, Angew. Chem. Int. Ed. 2008, 47 (43), 8170–8176.

(6)

Synthesis of the Cyclobutane Moiety of Providencin

T. Gaich, V. Arion, J. Mulzer, Heterocycles 2007, 74 (1), 855–862.

(5)

Synthetic Studies towards the Total Synthesis of Providencin

E. Schweizer, T. Gaich, L. Brecker, J. Mulzer, Synthesis 2007, 24, 3807–3814.

(4)

Metathesis reaction and olefin ring closing metathesis for organic synthesis

T. Gaich, E. Ohler, J. Mulzer, Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, Elsevier, Amsterdam, 2007, 207–269.
ISBN: 9780124095472

(3)

New Solutions to the C-12,13 Stereoproblem of Epothilones B and D; Synthesis of a 12,13-Diol-Acetonide Epothilone B Analog

T. Gaich, G.  Karig, H. J. Martin, J. Mulzer, Eur. J. Org. Chem. 2006, 15, 3372–3394.

(1)

Synthesis of Epothilones via a Silicon-Tethered RCM Reaction

T. Gaich, J. Mulzer, Org. Lett. 2005, 7 (7), 1311–1313.