List of Publications

 

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20

Non-canonical C16 Homoterpene Biosynthesis Widespread in Actinobacteria 

T. Reuter*, L. Dieminger*, S. Steidle, K. Zoller, M. Holocher, L. Zhou, D. Hanauska, K. Racz, L. Barra, Angew. Chem. Int. Ed. (2024), accepted.  

19

The structural basis of pyridoxal 5'-phosphate dependent beta-NAD alkylating enzymes

T. Awakawa*, T. Mori*, L. Barra*, Y. Ahmed, R. Ushimaru, Y. Gao, N. Adachi, T. Senda, T. Terada, D. J. Tantillo, I. Abe, Nat. Catal. (2024), 7, 1099 – 1108. 

18

Noncanonical Functions of Enzyme Cofactors as Building Blocks in Natural Product Biosynthesis

L. Barra, T. Awakawa, I. Abe, JACS Au (2022), 2, 1950 – 1963. 

17

β-NAD as a building block in natural product biosynthesis

L. Barra, T. Awakawa, K. Shirai, Z. Hu, G. Bashiri, I. Abe, Nature (2021), 600, 754 – 758.

16

Biosynthesis of Sulfonamide and Sulfamate Antibiotics from Actinomycetes

T. Awakawa*, L. Barra*, I. Abe, J. Ind. Microbiol. Biot. (2021), 48, kuab001.

15

Chemistry of fungal meroterpenoid cyclases

L. Barra, I. Abe, Nat. Prod. Rep. (2021), 38, 566 – 585.

14

Exploiting the Potential of Meroterpenoid Cyclases to Expand the Chemical Space of Fungal Meroterpenoids

T. Mitsuhashi,* L. Barra,* Z. Powers,* V. Kojasoy,* A. Scharf, A. Cheng, F. Yang, Y. Taniguchi, T. Kikuchi, M. Fujita, D. J. Tantillo, J. A. Porco Jr., I. Abe, Angew. Chem. Int. Ed. (2020), 59, 23772 – 23781.

13

Biomimetic Synthesis of Meroterpenoids by Dearomatization-Driven Polycyclization

Z. Powers, A. Scharf, A. Cheng, F. Yang, M. Himmelbauer, T. Mitsuhashi, L. Barra, Y. Taniguchi, T. Kikuchi, M. Fujita, I. Abe, J. A. Porco, Angew. Chem. Int. Ed. (2019), 58, 16141 – 16146.

12

An Unusual Skeletal Rearrangement in the Biosynthesis of the Sesquiterpene Trichobrasilenol from Trichoderma

K. Murai, L. Lauterbach, K. Teramoto, Z. Quan, L. Barra, T. Yamamoto, K. Nonaka, K. Shiomi, M. Nishiyama, T. Kuzuyama, J. S. Dickschat, Angew. Chem. Int. Ed. (2019), 58, 15046 – 15050.

11

Evolution and diversity of biosynthetic gene clusters in Fusarium

K. Hoogendoorn, L. Barra, C. Waalwijk, J. S. Dickschat, T. van der Lee, M. H. Medema, Front. Microbiol. (2018), 9, 1158.

10

Harzianone Biosynthesis by the Biocontrol Fungus Trichoderma

L. Barra, J. S. Dickschat, ChemBioChem, (2017), 18, 2358 – 2365.

9

Volatiles from the fungal microbiome of the marine sponge Callyspongia cf. flammea

L. Barra, P. Barac, G. M. König, M. Crüsemann, J. S. Dickschat, Org. Biomol. Chem. (2017), 15, 7411 – 7421.

8

Sceptrin – Enantioselective Synthesis of a Tetrasubstituted all-trans Cyclobutane Key Intermediate

L. Barra, J. S. Dickschat, Eur. J. Org. Chem. (2017), 4566 – 4571.

7

Discovery of a Mosaic-Like Biosynthetic Assembly Line with a Decarboxylative Off- Loading Mechanism through a Combination of Genome Mining and Imaging

M. M. Mohseni, T. Höver, L. Barra, M. Kaiser, P. C. Dorrestein, J. S. Dickschat, T. F. Schäberle, Angew. Chem. Int. Ed. (2016), 55, 13611 – 13614.

6

A method for investigating the stereochemical course of terpene cyclisations

P. Rabe, J. Rinkel, T. A. Klapschinski, L. Barra, J. S. Dickschat, Org. Biomol. Chem. (2016), 14, 158 – 164.

5

Thermal Rearrangement and EI-MS-Fragmentation Mechanism of (1(10)E,4E,6S,7R)-Germacradien-6-ol by 13C-Labeling Experiments

P. Rabe, L. Barra, J. Rinkel, R. Riclea, C. A. Citron, T. A. Klapschinski, A. Janusko, J. S. Dickschat, Angew. Chem. Int. Ed. (2015), 54, 13448 – 13451.

4

Structural Revision and Biosynthesis of Hypodoratoxide by 13C,13C-COSY-NMR

L. Barra, K. Ibrom, J. S. Dickschat, Angew. Chem. Int. Ed. (2015), 54, 6637 – 6640.

3

Volatiles from Nineteen Recently Genome Sequenced Actinomycetes

C. A. Citron, L. Barra, J. Wink, J. S. Dickschat, Org. Biomol. Chem. (2015), 13, 2673 – 2683.

2

Synthesis of Isotopically Labelled Oligoprenyl Diphosphates and Their Application in Mechanistic Investigations of Terpene Cyclases

C. A. Citron, P. Rabe, L. Barra, C. Nakano, T. Hoshino, J. S. Dickschat, Eur. J. Org. Chem. (2014), 7684 – 7691.

1

Pogostol Biosynthesis by the Endophytic Fungus Geniculosporium

L. Barra, B. Schulz, J. S. Dickschat, ChemBioChem (2014), 15, 2379 – 2383.

  *equal contribution