Biomineralization: Intrinsic details of the complex process

Biomineralization is the intricate process employed by living organisms to form minerals. Human orthopedic conditions, such as osteoporosis, are a direct consequence of poorly orchestrated biomineralization. Deciphering the molecular mechanism of this vital yet poorly understood process is thus essential for the development of therapeutic approaches. Using multiples simulations on amphiphilic peptides we identified the effects of various aspects of the peptide sequence (length, terminal, side-chains) on aggregate stability and ion-­peptide interactions.